COMPOSITION

Each 5 ml of suspension contain aluminum hydroxide dry gel 405 mg, magnesium hydroxide 100 mg, simethicone 125 mg.

THERAPEUTIC INDICATIONS

Diseases of digestive tract accompanied with raised and normal secretion function, meteorism (raised gases in intestines).
It is applied in combination with other medical products for:
- Ulcer of stomach and duodenal gut in aggravation phase;
- Acute gastritis, chronic gastritis in aggravation phase;
- Stomach and duodenal gut erosion; peptic ulcer; hernia of esophageal opening;
- Reflux-esofagitis;
- Duodenogastric reflux.
And also it is possible to use for discomfort and pain in epigastria, heartburn, and sour eructation because of poor nutrition, alcohol, coffee and nicotine abuse.

CONTRAINDICATIONS

- Hypersensitization to the components of the drug Simalgel;
- Clinically important impaired renal function (because of danger of increase of magnesium and aluminum ions concentration in blood serum, owing to delay of their elimination by kidneys);
- Children younger than 10 years.

DOSAGE AND ADMINISTRATION

For oral use.
For adults – 10 ml 4 times a day, 1 hour after meal and before sleeping (if it is not specified by the doctor). For reflux-esofagitis take the medicine in short time after meal.
The course of treatment is 2-3 months.
In case of incidental administration (discomfort because of wrong meal)-10 ml once.
A physician prescribes dosage for children older 10 years (usually ½ of the adult doze).

ADVERSE EFFECTS

Aluminum and magnesium intoxication may develop in patients with renal insufficiency. Diseases of bones and joints and Alzheimer's disease may exacerbate in elder patients. Effects from GIT such as taste disorder, nausea, vomiting, diarrhea, constipation, may occur rarely.

DRUG INTERACTIONS

Concomitant administration with tetracycline antibiotics, histamine H2-receptors blockers, digitalis glycosides, Fe salts, ciprofloxacin, phenothiazines, isoniazid, beta-blockers, indometacin and ketokenozole and others may attenuate therapeutic effect of Simalgel.

MANUFACTURED FORM

Oral suspension 300 ml in a glass vial.
One vial is in carton box with the leaflet and measuring cap.