Silarsil
(Silymarin)




COMPOSITION

Each capsule contains silymarin 70 mg or 140 mg.

THERAPEUTIC INDICATIONS

- Liver lesion during alcoholism;
- Chronic liver intoxication (including professional) by halogenated carbohydrates, heavy metals combinations and their prophylaxis;
- Drug liver lesions (particularly by some psychotropic agents, tuberculostatics, peroral contraceptives, paracetamol, some antibiotics and immunosuppressants, anesthetic drugs) and their prophylaxis;
- Chronic hepatitis of non-viral aetiology;
- Cirrhosis (in context of complex therapy);
- Supporting therapy during chronic inflammatory liver diseases and cirrhosis;
- State after infectious toxic hepatitis;
- Dystrophy and fatty liver infiltration;
- Correction of disorders of lipidic exchange.

CONTRAINDICATIONS

- Increased sensibility to drug components.

ADVERSE EFFECTS

From digestive system: seldom – dyspepsia, diarrhea.
Dermatological reactions: in individual cases – skin manifestations of allergic reactions.
Other: in individual cases – exacerbation of existing vestibular disorders.

DOSAGE AND ADMINISTRATION

Administer the drug orally after meal, not chewing, washing down with small amount of water.
Depending on disease severity, stage and type, the daily dose for grown-up is 70-140 mg, divided on 3 applications. Daily dose can be increased up to 420 mg a day. For supportive therapy 70-140 mg are prescribed 2 times a day.
Daily dose for children from 12 years is 5 mg/kg of body weight, divided on 2-3 administrations.
Treatment course is not less than 3 months.

PREGNANCY AND LACTATION

The drug is prescribed only by strict indications and after thorough assessment of benefit/risk ratio at pregnancy and during lactation period.

MANUFACTURED FORM

Hard gelatin capsules 70 mg. 10 capsules in blister. 3 blisters in carton box with enclosed leaflet.
Hard gelatin capsules 140 mg. 10 capsules in blister. 3 blisters in carton box with enclosed leaflet.

Alimentary Tract and Metabolism

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