D-Calcin (Calcium-magnesium inositohexaphosphate & Calcium gluconate & Vitamin D2)
COMPOSITION
5 g of granules contain:
Calcium-magnesium inositohexaphosphate 125 mg;
Calcium gluconate 375 mg;
Vitamin D2 3000 IU.
THERAPEUTIC INDICATIONS
- Prophylaxy and treatment of rachitism:
disorders of calcium metabolism accompanied with osteopathy, spasmophilia,
disorders of bone formation and dental eruption, growth retention in period of
intensive development of the body;
- Prophylaxy of osteoporosis of different genesis;
- Conditions during which demand in vitamin D and calcium increases:
Breast-feeding children or children with inadequate fresh air intake;
Bottle-feeding children with vitamin D deficiency;
Malabsorption syndrome, chronic diarrhea, gastrectomy;
Neurasthenia;
Steatorrhea;
- Patients facing therapy with hormones, anticonvulsants, immune suppressors,
aluminium-containing antacids, diuretics.
CONTRAINDICATIONS
- Hypercalcemia;
- Hypervitaminosis D;
- Hyperphosphatasemia;
- Hyperparathyroidism.
ADVERSE EFFECTS
The drug is generally well tolerated.
During long-term use hypercalcemia is possible.
DOSAGE AND ADMINISTRATION
D-Calcin is taken orally.
Prophylaxy of osteoporosis: 1000-2000 IU daily (1/4-1/2 of measuring cup).
Prophylaxy of rachitism and osteomalation: 400 IU daily (1 coffee spoon).
Treatment of vitamin D2 nutrition deficiency, rachitism and osteomalation: in
adults 1000-2000 IU daily (1/4-1/2 of measuring cup), in children 1000-4000 IU
daily (1/4-1 of measuring cup).
Treatment should last over several months. After completing treatment course if
necessary can be followed by taking preventive doses of vitamin D (400 IU) for
adults and children.
Osteomalation in patients with long-term intake of anticonvulsants: in adults
1000-4000 IU (1/4-1 of measuring cup) daily, in children 1000 IU (1/4 of
measuring cup) daily.
DRUG INTERACTIONS
Vitamin A, tokoferol, hexuronic acid, pantothenic
acid, tiamin, riboflavin decrease the drug action. In case of vitamin D
hypervitaminosis the potantiation of cardiac glycoside and risk of arrhythmia is
possible. By the action of barbiturates (including phenobarbital), primidon,
phenytoin demand of ergocalciferol can increase (increase the speed of
metabolism). In case of simultaneous intake with sodium fluoride interval should
be not less than 2 hours. The simultaneous administration with other
polyvitaminic complexes containing calcium and vitamin D should be avoided.
PRAGNANCY AND LACTATION
During the pregnancy intake of high doses of
vitamin В is not recommended. During breast–feeding the product should be given
with caution.
MANUFACTURED FORM
Granules 75 g. in plastic bottle with
dose-measuring cup with leaflet in carton box.
|